TnCentral is a Web-resource for prokaryotic transposons, their passenger genes, and their
host organisms. It provides a variety of Search functions, BLAST functions for TnCentral and
other related databases and a summary page with detailed annotation and a descriptive
graphic for each transposon. It also makes available stand-alone scripts for identifying
different transposons in genomic sequence data.
TnCentral is a database of annotated prokaryotic (bacterial and archaeal) transposons (Tn) of different types retrieved from a variety of sources (literature, Genbank).
TnCentral has also been supplemented by in-house software permitting database mining of Tn3 family and Compound Tn. Additional transposon groups will be added over time.
The database can be searched for individual Tn, and their derivatives such as MICs and MITES or Tn groups,
passenger genes such as antibiotic (AbR) or heavy metal resistance, bacterial host, geographical location and date of isolation.
There is a Blast facility which allows comparison of users submitted DNA sequences with Tn in TnCentral.
The developers wish to acknowledge useful discussions with members of the ISfinder (https://www-is.biotoul.fr/) team (P. Siguier, E. Gourbeyre, J. Perochon).
The TnCentral banner is modified from L. Lavatine, S He, A Caumont-Sarcos, C Guynet, B Marty, M Chandler and B Ton-Hoang (2016) Single strand transposition at the host replication fork NAR doi: 10.1093/nar/gkw661.
We also acknowledge the contributions of O. Barabas, A. Hickman, F. Dyda , and D. Lane and of previous members of the ex-Chandler lab in Toulouse: A. Achard, M. Betermier, A. Caumont-Sarcos, A. Corneloup, G. Duval-Valentin, JM. Escoubas, P. Gamas, E. Guegen, C. Guynet, L. Haren, S. He, L. Lavatine, C. Loot, B. Marty, C. Normand, P. Rousseau, N. Pouget, B. Ton Hoang, C. Turlan, AM. Varani, D. Zerbib.